• Swallow the tablet whole with water.
• Avoid breaking or chewing the tablet.
• Take the tablet at the same time each day for optimal results.
• Do not discontinue the medication suddenly without consulting your doctor.
Ranonux 500 Tablet is primarily indicated for the management of chronic stable angina, a cardiac condition that manifests as chest pain. This medication belongs to the class of anti-anginal medicines.
Ranonux 500 Tablet is prescribed for:
• Management of chronic stable angina
• Improvement of exercise tolerance in angina patients
• Use in patients who are intolerant to other conventional anti-anginal medications
• Swallow the tablet whole with water.
• Avoid breaking or chewing the tablet.
• Take the tablet at the same time each day for optimal results.
• Do not discontinue the medication suddenly without consulting your doctor.
Ranonux 500 Tablet is taken orally.
The side effects of Ranonux 500 Tablet may include:
• Nausea
• Vomiting
• Headache
• Dizziness
• Constipation
Ranonux 500 Tablet contains ranolazine (500 mg), which functions as follows:
• Sodium Current Inhibition: Ranolazine inhibits the late phase of the inward sodium current in cardiac myocytes, reducing intracellular sodium accumulation.
• Calcium Overload Prevention: By limiting sodium entry, it indirectly reduces calcium influx in the heart muscle cells, thus preventing calcium overload.
• Cardiac Efficiency: This modulation of sodium and calcium levels enhances the efficiency of cardiac muscle function during episodes of insufficient oxygen supply.
Exercise caution and consult your doctor before taking Ranonux 500 Tablet during pregnancy.
Discuss with your doctor before using Ranonux 500 Tablet while breastfeeding.
Avoid alcohol as it may exacerbate side effects such as dizziness.
Ranonux 500 Tablet is contraindicated in patients with liver impairments.
Use with caution if you have renal impairments. Consult your doctor prior to use.
This medication may cause dizziness. Avoid operating machinery or driving if you experience these effects.
Do not take if you are allergic to ranolazine or any excipients in the tablet.
Ranonux 500 Tablet is not recommended for individuals under 18 years unless prescribed by a doctor.
Elderly patients should use Ranonux 500 Tablet under medical supervision due to increased susceptibility to side effects.
Drug-Drug Interactions
• Antifungals: May alter the action of Ranonux 500 Tablet, resulting in increased side effects.
• Antiarrhythmics: Can affect the efficacy of Ranonux 500 Tablet and heighten the risk of side effects.
• Antiretrovirals: Can enhance blood levels of ranolazine, amplifying its effects.
• Statins: May significantly increase statin levels in the blood, potentially causing liver and kidney damage.
Drug-Food Interactions
• Grapefruit: Grapefruit or grapefruit juice can elevate ranolazine levels in the blood, thereby increasing the risk of adverse effects.
Drug-Disease Interactions
• Long QT Syndrome: Ranonux 500 Tablet may prolong the QT interval, requiring caution in patients with long QT syndrome.
Daily Dose
• Your doctor will determine the daily dose of Ranonux 500 Tablet based on your condition and response to treatment. Always adhere to the prescribed dosage.
Missed Dose
• If you miss a dose, take it as soon as you remember.
• If it is almost time for the next dose, skip the missed dose and continue your regular schedule.
• Do not double the dose.
Overdose
• The symptoms of an overdose may include nausea, dizziness, or headache. Seek immediate medical attention if an overdose occurs.
• Store at room temperature, preferably below 30°C.
• Keep the medication out of direct sunlight, heat, and moisture.
• Ensure it is out of the reach of children.
• Use before the expiration date on the package.
• Engage in regular, gentle exercise such as walking or swimming to improve heart efficiency and manage angina.
• Adopt a heart-healthy diet low in saturated fats and cholesterol, including fruits, vegetables, whole grains, and lean proteins.