Tofnux 5 Tablet is primarily utilised to manage rheumatoid arthritis, a chronic inflammatory condition affecting the joints. This medicine is categorised under Janus kinase inhibitors, a class of medications designed to modulate immune responses and reduce inflammation.
This medicine is prescribed for the following:
• Rheumatoid arthritis
• Ulcerative colitis
• Psoriatic arthritis
• Polyarticular course juvenile idiopathic arthritis
• Swallow the tablet whole with a glass of water.
• Avoid crushing or chewing the tablet.
• Take the medication at regular intervals as directed by your doctor.
• Do not adjust the dose without consulting your doctor first.
• If you have any questions or concerns, consult your doctor.
Tofnux 5 Tablet is taken orally.
Common side effects associated with this tablet may include:
• Diarrhoea
• Headache
• Upper respiratory tract infections
• Nasopharyngitis
This medication contains tofacitinib (5 mg), which operates through the following mechanisms:
• Janus Kinase Inhibition: Tofacitinib inhibits Janus kinases, which are involved in inflammation and joint damage.
• Reduction of Inflammation: By blocking these proteins, tofacitinib effectively reduces inflammation and symptoms of inflammatory disorders.
• Immune Response Regulation: Tofacitinib regulates the overactive immune response observed in rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. This helps manage these conditions.
Exercise caution and consult your doctor before taking Tofnux 5 Tablet.
This tablet is contraindicated for breastfeeding women; consult with a doctor.
Limit alcohol consumption as it may exacerbate side effects.
Routine liver function test is advised with this tablet. Use in severe liver impairment is not recommended.
Moderate to severe kidney impairment patients require dosage adjustment.
This tablet may cause dizziness or drowsiness; exercise caution when driving or operating machinery.
If you are allergic to tofacitinib or any other ingredients in the tablet, do not take this medicine without consulting a doctor.
Prescribed for age 2 years and older as an oral solution in the dosage as advised by pediatrician.
Should take this tablet under medical supervision due to increased sensitivity to side effects.
Drug-Drug Interactions
• Immunosuppressants: May increase the risk of infection due to a weakened immune system.
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Can enhance the potential for gastrointestinal issues such as stomach ulcers and bleeding.
Drug-Food Interactions
• High-fat Meals: Can increase the absorption of tofacitinib, potentially leading to higher concentrations in the bloodstream.
• Grapefruit: May enhance medication levels, increasing the risk of side effects.
Drug-Disease Interactions
• Cardiovascular Disease: The tablet might increase the risk of heart-related events.
Daily Dosage
• Tofnux 5 Tablet should be taken as advised by your doctor, based on your condition and response to the medication.
Missed Dose
• If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose. Do not double up on doses without consulting your doctor.
Overdose
• Symptoms of overdose may include headache, diarrhoea, and nausea. Contact your doctor immediately if an overdose is suspected.
• Store at room temperature, ideally below 30°C.
• Keep in original packaging, tightly sealed.
• Protect from direct sunlight and moisture.
• Keep out of reach of children.
• Consider incorporating foods rich in omega-3 fatty acids, such as fish and nuts, to help reduce inflammation.
• Engage in regular gentle exercise like swimming or walking to manage symptoms and promote general well-being.
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