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Direction of Use
• Swallow the tablet whole with a glass of water.
• It can be taken with or without food.
• Do not crush, chew, or break the tablet.
• Do not alter your dosage or discontinue use without consulting your doctor.
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Antiepileptic
Valprat Chrono 500 Tablet 10
Valprat Chrono 500 Tablet is primarily used to manage a range of seizure disorders, including epilepsy. It belongs to the class of medicines known as antiepileptic and mood-stabilising agents.
COMPOSITION
Sodium Valporate/Valproic acid
500 Mg
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Product information
Uses
Direction of Use
Route of Administration
Side Effects
How it Works?
Safety Measures & Warnings
Interactions
Dosage
Storage
Diet & Lifestyle Advice
Quick Facts
Uses
Valprat Chrono 500 Tablet is prescribed for:
• Managing various types of seizures and epilepsy
• Controlling manic episodes in adults with bipolar disorder
• Preventing migraine headaches in adults
Route of Administration
Valprat Chrono 500 Tablet is taken orally.
Side Effects
Valprat Chrono 500 Tablet may have the following common side effects:
• Nausea
• Vomiting
• Dizziness
• Drowsiness
• Tremors
How it Works?
Valprat Chrono 500 Tablet contains sodium valproate/valproic acid (500 mg), which acts in the body as follows:
• Increasing GABA Levels: Sodium valproate/valproic acid enhances the concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, thereby reducing neuronal excitability in the brain.
• Reducing Neuronal Excitation: It suppresses the excessive firing of neurons, thereby controlling seizure activity.
• Modulating Channel Activity: This medicine modulates the activity of voltage-gated sodium channels and T-type calcium channels, contributing to its therapeutic effects.
• Enhancing GABA Synthesis: By inhibiting the catabolism of GABA, it ensures a stable presence of this neurotransmitter in the brain.
Safety Measures & Warnings
Pregnancy
This tablet is not recommended during pregnancy, particularly in the first trimester, due to the risk of birth defects.
Breastfeeding
The content of this medication is excreted in breast milk and can cause sedation, irritability, poor feeding, and other issues in infants.
Alcohol
Avoid alcohol as it may exacerbate side effects such as drowsiness and liver damage.
Liver
Not recommended for liver patients.
Kidney
Dosage adjustment not required but patient should be monitored for adverse effects.
Using Machines & Driving
This medicine may cause drowsiness or blurred vision; avoid such activities until you know how it affects you.
Allergy
Do not take if you have an allergy to valproate or any other ingredient in the tablet.
Children
This tablet can cause risk of hepatotoxicity especially in children less than 2 years of age.
Older Patients
Initially, lower doses are recommended due to vulnerability to adverse effects because of age-related changes.
Interactions
Drug-Drug Interactions
• Blood Thinners: May increase the risk of bleeding.
• Antibiotics: Can decrease the efficacy of sodium valproate.
• Antacids: May increase sodium valproate levels, causing more side effects.
• Epilepsy Medicines: Could alter levels and efficacy.
• Cholesterol-Lowering Agents: Might reduce absorption.
Drug-Food Interactions
• High-Fat Meals: May slow down the absorption of this tablet.
Drug-Disease Interactions
• Urea Cycle Disorders: The condition may be exacerbated.
• Porphyria: Could trigger an attack.
• Mitochondrial Disorders: Use might lead to liver damage.
Dosage
Daily Dosage
• Take this tablet as prescribed by your doctor.
Missed Dose
• If you forget to take a dose, take it as soon as you remember.
• If it is nearly time for your next dose, skip the missed dose.
Overdose
• Common symptoms of overdose include nausea, dizziness, and weakness.
Storage
• Store at room temperature.
• Keep in a tightly closed container, protected from light and moisture.
• Keep out of reach of children.
Diet & Lifestyle Advice
• For epilepsy: Maintain a regular sleep schedule to prevent seizures.
• For bipolar disorder: Incorporate stress management techniques like meditation.
Quick Facts
Drug Category
Antiepileptic, Mood Stabiliser
Therapeutic Category
Antiepileptic
Available Dosage Types
Tablet
Habit Forming
No
Ailment
Epilepsy, Manic Episodes, Migraine Prevention
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Frequently asked questions
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What is Valprat Chrono 500 Tablet used for?
How does Valprat Chrono 500 Tablet work?
Can I consume alcohol while taking Valprat Chrono 500 Tablet?
Is Valprat Chrono 500 Tablet habit-forming?
What should I do if I miss a dose of Valprat Chrono 500 Tablet?