Rentrex 20 Capsule is primarily used to manage severe nodular acne that has not responded to other available treatments, including antibiotics. It belongs to the class of medicines known as retinoids.
Rentrex 20 Capsule is used for the following:
• Managing severe nodular acne that has not responded to other treatments
• Managing recalcitrant nodular acne
• Handling acne that has been unresponsive to conventional therapy
To use Rentrex 20 Capsule effectively, adhere to the following instructions:
• Take the capsule orally as directed by your doctor.
• Do not alter or exceed the prescribed dose without consulting your doctor.
• Avoid discontinuing the medication without your doctor's guidance.
• Follow the dietary guidelines recommended by your doctor.
Rentrex 20 Capsule is taken orally.
Rentrex 20 Capsule may have the following common side effects:
• Dry, chapped lips
• Dry skin
• Dry eyes
• Dry nose that may lead to nosebleeds
Rentrex 20 Capsule contains isotretinoin (20 mg), which functions in the following capacities:
• Reduction of Sebaceous Gland Activity: Isotretinoin significantly diminishes the production of sebum, the skin's natural oil, by approximately 90% or more. This reduction inhibits the growth of acne bacteria.
• Normalization of Keratinisation: Isotretinoin aids in normalising the process of skin cell growth and shedding, which prevents blocked pores and reduces comedone formation.
• Reduction of Cutibacterium acnes: By changing the skin's environment to be less anaerobic, it indirectly diminishes the population of Cutibacterium acnes bacteria on the skin.
• Anti-inflammatory Effects: Isotretinoin exhibits anti-inflammatory properties, though the exact mechanisms remain unclear.
Rentrex 20 Capsule is contraindicated during pregnancy. It is crucial to consult your doctor if you are pregnant or planning to conceive before commencing this medicine.
It is not advisable to use Rentrex 20 Capsule while breastfeeding. Discuss the potential risks and benefits with your doctor.
Avoid alcohol consumption while taking Rentrex 20 Capsule, as both isotretinoin and alcohol may adversely affect liver function.
Caution is advised if you have liver problems, particularly chronic or active liver disease. Isotretinoin may influence liver function.
Consult your doctor before using Rentrex 20 Capsule if you have a history of kidney problems.
Isotretinoin may impair night vision; therefore, exercise caution when driving at night or operating machinery.
Do not take this medicine if you are allergic to isotretinoin, vitamin A, or any component of the capsule.
Exercise caution when using Rentrex 20 Capsule in children under 12 years due to the potential for long-term skeletal implications. Always consult your doctor before administering this medicine to a child.
Older patients should take Rentrex 20 Capsule under medical supervision as they may be more susceptible to side effects. Your doctor will provide guidance based on your individual health status.
Drug-Drug Interactions
• Vitamin A Supplements: Concurrent use with Rentrex 20 Capsule may lead to vitamin A overdose, resulting in symptoms such as dizziness and nausea.
• Tetracycline Antibiotics: Combining these medicines can increase the risk of intracranial hypertension, leading to severe headaches and vision disturbances.
• Systemic Corticosteroids: Co-administration with Rentrex 20 Capsule may result in bone density loss or osteoporosis.
Drug-Food Interactions
• High-fat Meals: Taking Rentrex 20 Capsule with a high-fat meal can enhance the absorption of isotretinoin, potentially increasing its effects and side effects.
Drug-Disease Interactions
• Diabetes: Isotretinoin may affect blood sugar control, necessitating close monitoring of glucose levels.
• Osteoporosis or Osteomalacia: Patients with these conditions may experience increased bone pain or a higher risk of fractures.
• Existing Skeletal Hyperostosis: Rentrex 20 Capsule may exacerbate this condition, which involves abnormal growth of bone.
Daily Dose
• The daily dose of Rentrex 20 Capsule should be taken as advised by your doctor. Adhering to the prescribed dosage is crucial, as it may vary based on the severity of your condition and your response to the medication.
Missed Dose
• If a dose is missed, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.
Overdose
• Common symptoms of Rentrex 20 Capsule overdose include nausea, vomiting, and headaches. If these symptoms persist or worsen, seek medical attention promptly.
• Store Rentrex 20 Capsule at a temperature below 25°C.
• Keep the capsules away from direct light
• It is important to keep it out of reach of children.
• Ensure the medicine is used before the expiry date indicated on the pack.
• Maintain a balanced diet rich in fruits, vegetables, and whole grains to support your body while taking Rentrex 20 Capsule. Antioxidants found in these foods may help reduce inflammation and promote clearer skin.
• Avoid excessive sun exposure. When outdoors, use sunscreen and wear protective clothing to prevent sunburn and protect your sensitive skin.
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